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MPTP NEUROTOXICITY SYNDROME
Descriptors Found:
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DeCS
Descriptor
English
:
MPTP Poisoning
Descriptor
Spanish
:
Intoxicación por MPTP
Descriptor
Portuguese
:
Intoxicação por MPTP
Synonyms
English
:
MPTP Neurotoxicity Syndrome
Tree Number:
C10.228.140.079.862.800.300
C10.228.662.600.700.250
C10.720.606
C25.723.705.400
Definition
English
:
A condition caused by the neurotoxin MPTP which causes selective destruction of nigrostriatal
dopaminergic neurons
. Clinical features include irreversible parkinsonian signs including rigidity and bradykinesia (
PARKINSON DISEASE
, SECONDARY). MPTP
toxicity
is also used as an animal model for the study of
PARKINSON DISEASE
. (Adams et al., Principles of
Neurology
, 6th ed, p1072;
Neurology
1986 Feb;36(2):250-8)
See Related
English
:
1-Methyl-4-phenylpyridinium
History Note
English
:
2000
Allowable Qualifiers
English
:
BL
blood
CF
cerebrospinal fluid
CI
chemically induced
CL
classification
CO
complications
CN
congenital
DI
diagnosis
DH
diet therapy
DT
drug therapy
EC
economics
EM
embryology
EN
enzymology
EP
epidemiology
EH
ethnology
ET
etiology
GE
genetics
HI
history
IM
immunology
ME
metabolism
MI
microbiology
MO
mortality
NU
nursing
PS
parasitology
PA
pathology
PP
physiopathology
PC
prevention & control
PX
psychology
RA
radiography
RI
radionuclide imaging
RT
radiotherapy
RH
rehabilitation
SU
surgery
TH
therapy
US
ultrasonography
UR
urine
VE
veterinary
VI
virology
Record Number:
34225
Unique Identifier:
D020267
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS